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Drug withdrawal syndrome could manifest on abrupt cessation of therapy or dose reduction. Every time a affected person not requires therapy, it truly is recommended to taper the dose gradually to minimise indicators of withdrawal. Tapering from the significant dose may well take weeks to months.four.six Fertility, pregnancy and lactation Pregnancy

There won't be any conventional opioid tapering schedules which are suited to all clients. Very good medical apply dictates a affected individual-unique decide to taper the dose on the opioid little by little. For individuals on OXYCONTIN that are bodily opioid-dependent, initiate the taper by a sufficiently small increment (e.To reduce the potenti